In appreciation of R& D contributions based on research publication in Scopus database, University of Kerala was selected as one of performing university by Government of India and provided substantive research grant under PURSE Scheme by Department of Science & Technology during 2011-2016. Realising that scientific instruments with cutting-edge technology are vital for pursuing research in many areas of modern science and technology, University of Kerala under Plan funds constructed a two storied building to house the procured sophisticated equipments under one roof. The Sophisticated Instrumentation and Computation Centre (SICC) at Kariavattom campus is a new and exciting initiative with broad range of state of-the-art analytical instruments purchased under PURSE Scheme and various other sources. The centre represents one of the largest commitments for research in the history of the university and will carry forward decades of research into new realms of application and discovery.
ICP-MS (Thermo Scientific ICAP Qc)
The iCAP Qc offers uniquely reliable cell mode performance and is configured for high quality analyses in routine, high-throughput laboratories, such as those specialising in environmental analysis, food quality control and geo-chemical exploration. With self-aligning injector, cone and lens assemblies, unparalleled plasma and collision cell stability and improved resistance to heavy sample matrices, the iCAP Q requires less maintenance and delivers accurate results even in challenging and complicated sample conditions. The iCAP Q is the only ICP-MS system to include proprietary QCell technology combining proven He KED (kinetic energy discrimination) interference reduction capabilities with a flatapole low mass cut-off. In comparison with higher-order multipole systems used in collision cells,the flatapoles in the QCell provide a low mass cut off that stops unwanted species from passing to the quadrupole mass filter. This provides complete collision cell reliability, even with new, complicated sample matrices. Elements like As and Hg can be analysed in ICAP Q c without hydride ion generator.
Spectral Confocal Microscope(SCM)
Confocal microscope has become a power full tool of choice for researchers interested in serious imaging of cell structure and function. These microscopes revolutionised our view of cells and became a major instrument in unravelling the complexities of the morphology and dynamics of cells and tissues. Initially it was used to observe the general spatial distribution of usually one or two fluorescent labelled structure or cell population in living or fixed samples. Now researchers can distinguish between two closely spaced structures within a specific organelle such as visualising RNA polymerase II mediated transcription sites associated with speckles in the nucleus. High resolution confocal microscopy has been used during in situ hybridisation to localise specific gene sequences to specific chromosomes. With the recent technological advances confocal microscopes have opened a new world to biologists interested in the dynamic complexities of the cell and to the researchers in life sciences. The microscope was purchased and installed at the New Sophisticated Instrumentation and Computation centre in March 2016. With the synergies of multi band spectral detector, acousto-optical beam splitter (AOBS) and super sensitive Leica HyD the microscope provide maximum photon efficiency and gapless spectral detection.This superior sensitivity directly translate into reduced laser power for cell viability and resolution. The AOBS (Acousto-Optical Beam Splitter) is a completely transparent, active TeO2 crystal, which offers maximum photon efficiency. An acoustic wave coupled into the crystal changes its transmission properties. It switches within microseconds by simply changing the radio frequency of the wave. This makes the AOBS a uniquely flexible, efficient, and fast beam splitter. The AOBS can accommodate up to eight reflection bands.
High Performance Computing Facility
The Campus Computing Facility is a dedicated Central Computing Facility (CCF) which provides high performance computing facility to faculty and students alike to take up computationally intensive research problems. Computational science has become the third pillar of scientific discovery, complementing theory and physical experimentation, allowing scientists to explore phenomenon that are too big, small, fast, or dangerous to investigate in the laboratory. The Linux cluster (parallel computer) at CCF is dedicated for the researchers to make full use of this important technology. For easy access and better utilization of these facilities, a series of training programmes and workshops are being carried out on various aspects of scientific computing. CCF has a well equipped computer laboratory with 50 Desktop computers and a high performance computing cluster with 10 nodes of 1 teraflops of computing power. Currently CCF extends facility to research work on Computational Chemistry, Social Network Analysis, Data Analytics, Computational Biology etc.
Two extra-departmental elective courses on parallel programming and data analytics are currently conducted at CCF. It also provide an off campus access to e-resource as well as learning management system through moodle .